Unlock rapid, high-precision protein charge characterization with the ProteinSimple iCE3 Analyzer, complete with the cIEF MicroInjector and Next Autosampler—a gold-standard solution for capillary isoelectric focusing (cIEF) in modern biopharmaceutical and biologics laboratories.

Designed for accurate, reproducible protein charge variant analysis, the iCE3 system delivers exceptional resolution and sensitivity for monoclonal antibodies, biosimilars, fusion proteins, and other therapeutic proteins. Its advanced cIEF technology enables detailed profiling of acidic and basic isoforms with minimal sample consumption and reduced hands-on time, making it ideal for R&D, process development, formulation studies, and quality control environments.

Key Capabilities & Advantages

• High-resolution capillary isoelectric focusing (cIEF) for precise protein charge heterogeneity analysis

• Fully automated workflow when paired with the Next Autosampler, improving throughput and consistency

• Flexible sample handling, supporting both 96-well plates and 11 mm vials

• Active temperature control for enhanced run stability and reproducibility

• Compact laboratory footprint, ideal for space-constrained biotech and pharma labs

• Low sample volume requirements, preserving valuable protein materials

• Scalable and automation-ready, suitable for routine analysis or high-throughput workflows

The cIEF MicroInjector ensures consistent and accurate sample introduction, reducing variability and improving method robustness. Combined with the Next Autosampler, the system enables unattended operation, making it a powerful solution for labs seeking efficiency without compromising analytical performance.

Manufacturer Information

The iCE3 Analyzer was developed by ProteinSimple, a recognized leader in protein characterization technologies and now part of Bio-Techne, a globally trusted life science instrumentation company. ProteinSimple systems are widely adopted across biotech, pharmaceutical, academic, and contract research organizations for their reliability, ease of use, and data quality.

Software & Computer Disclosure

Please note:

• The computer and software license are not included with this listing

• The computer shown in photos was used for testing purposes only

• The computer that ships with the unit will be included, however software access cannot be guaranteed, as login credentials were not provided

• The buyer will need to purchase or transfer a software license directly from the manufacturer

Condition & Warranty

• System has been tested and verified for proper operation

• Includes a 30-day warranty for added confidence and peace of mind

This ProteinSimple iCE3 cIEF system is an excellent choice for laboratories seeking fast, reliable, and highly reproducible protein charge analysis, backed by a proven platform trusted throughout the biopharmaceutical industry.